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We actively collaborate with our colleagues in the University of Iowa Institute for Vision Research in the study of blinding diseases including Bardet-Biedl syndrome, Best disease, Stargardt disease, Leber congenital amaurosis, retinitis pigmentosa, choroideremia, glaucoma, and other acquired and inherited diseases of the retina.

Our laboratory employs a multidisciplinary approach involving donated human eyes, cell culture models including induced pluripotent stem cells, mouse models, and anatomical, molecular, and functional studies. It is our goal to use this knowledge to improve treatments and ultimately develop cures for the millions of individuals whose sight is threatened by retinal and choroidal diseases.

Recent News

  • Wed, 11/06/2024 - 10:45

    Our lab recently published a new study involving 99 human donor eyes in which degenerating blood vessels were measured in eyes with healthy aging, early stage macular degeneration, and late stage dry macular degeneration (geographic atrophy).

  • Nate-Mullin-with-Mentors_3-8-2024
    Tue, 04/02/2024 - 16:45

    The lab is extremely proud of MD/PhD student Nathaniel K. Mullin (Interdisciplinary Graduate Program in Genetics) who successfully defended his dissertation, “Cellular and molecular consequences of genetic variants in inherited retinal disease”.

  • Mon, 10/30/2023 - 12:00

    In a recent paper by Voigt et al, we studied how gene expression is altered in focal areas of pathology by performing spatial RNA sequencing on a human donor eye with macular neovascularization as well as a healthy control donor.