New Publication on the Complement System in AMD

Sunday, January 23, 2022 - 15:30

Our lab recently published a new report on the role of local synthesis of the Complement Factor H gene product in protecting choroidal endothelial cells from deposition of the complement MAC complex, a major source of cellular injury in AMD. Kelly used immortalized choroidal endothelial cells and induced pluripotent stem cells to determine that local expression of the Factor H protein is sufficient to increase cellular protection.