We actively collaborate with our colleagues in the University of Iowa Institute for Vision Research in the study of blinding diseases including Bardet-Biedl syndrome, Best disease, Stargardt disease, Leber congenital amaurosis, retinitis pigmentosa, choroideremia, glaucoma, and other acquired and inherited diseases of the retina.

Our laboratory employs a multidisciplinary approach involving donated human eyes, cell culture models including induced pluripotent stem cells, mouse models, and anatomical, molecular, and functional studies. It is our goal to use this knowledge to improve treatments and ultimately develop cures for the millions of individuals whose sight is threatened by retinal and choroidal diseases.

Recent News

  • 2020-Vector-Photo-Contest_Mullins-Lab-Submission_Confocal-Projection_Human-Choroid_UEA-CD45-Iba1
    Wed, 12/09/2020 - 15:00

    Research Associate and Lab Manager Miles Flamme-Wiese was honored in the 2020 Vector Laboratories Photo Contest when his submission was selected as one of ten contest winners.

  • Thu, 11/14/2019 - 12:00

    In November, our laboratory published the first report detailing gene expression patterns of the human retinal pigment epithelium and choroid at the single cell level. We identified 11 categories (clusters) of cells, including melanocytes, Schwann cells and immune cells.

  • Labeling of healthy blood vessels (red) in a healthy eye (left) and an eye with geographic atrophy (right). Note the loss of choriocapillaris vessels (CC) in the eye with geographic atrophy.
    Wed, 08/14/2019 - 09:00

    The lab recently published a study in which blood vessel density was examined in 143 human donor eyes with healthy aging, early stage age-related macular degeneration, and advanced "dry" macular degeneration (geographic atrophy).